Lymphedema is a painful swelling in the arms or legs most common after cancer treatment. When the lymphatic system is compromised, fluid can’t drain properly and builds up—but it isn’t just limited to cancer. Lymphedema can occur after severe trauma, kidney disease, orthopedic surgery, stroke, or due to vein issues. If you think your swelling is abnormal or it lasts for more than two weeks, see your doctor. Left untreated, lymphedema can cause unsightly skin changes, immobility and severe infections. Though there is currently no cure, symptoms can be treated with physical and occupational therapy, manual massage, compression garments, exercise, and skin care.